N, N-Dimethylformamide
brief introduction
Chemical name: N two, N- dimethyl formamide
Chinese alias: two methyl fumarate
English Name: N, N-Dimethylformamide
English alias: DMF; N N- dimethylformamide absolute over, mol. sieve (H2O <0.01%); N, N-dimethylformamide B&J brand L N N-Dimethylformamide, 4; DMF; DIMETHYL FORM.L WATER, S SEAL; Formdimethylamide
Molecular formula: C3H7NO
Molecular weight: 73.09
Density: 0.9487
CAS number: 68-12-2
The main purpose
Two DMF is a wide range of chemical raw materials, is a widely used good solvent. Two methyl formamide as good solvent for various polymers such as polyethylene, polyvinyl chloride, polyacrylonitrile, polyamide, polyurethane, can be used for the synthesis of wet spinning polyacrylonitrile fiber synthetic fiber; used plastic film; also can be used for the removal of paint remover paint; it can dissolve some low solubility of the pigment, the pigment characteristics with the dye. Two DMF for aromatics extraction and separation for recovery of butadiene from carbon four fraction separation and recovery of isoprene from carbon five fraction, but also can be used as effective reagents for separation of non hydrocarbon components from paraffin wax. The solubility of benzene between two formic acid and terephthalic acid have good selectivity, solubility between two formic acid in two methyl formamide than terephthalic acid, solvent extraction or partial crystallization in two formic acid formamide, separated. In the petroleum chemical industry, two DMF can be used as gas absorbent, used for separation and purification of gas. In organic reactions, two DMF is not only widely used as the reaction solvent, is also the important intermediate of organic synthesis. The pesticide industry can be used in the production of Chlordimeform; pharmaceutical industry can be used in the synthesis of iodine amine pyrimidine, doxycycline, cortisone, vitamin B6, iodine glycosides, monopar, antiminth, N- formylmerphalan, sarcolysin, 3P, Bian mechlorethamine, lomustine, furosemide fluorouracil, tranexamic acid, dexamethasone, divided times megestrol, trithioanethol, chlorpheniramine and so on. With the catalysis of two DMF dehydrohalogenation in hydrogenation, dehydrogenation and dehydration and reaction, the reaction temperature is reduced, the product purity increases.
Although the "universal solvent", but also has its limitations. High boiling point of about 154 DEG C. If more appropriate as many polymer solvent, but should be carefully selected in organic synthesis, solvent removal easy to hit the net situation. Can be miscible with water, solvent recovery method is simple and is difficult to dehydration. If you do not consider the cost, you can wash.